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Prospective, long-term evaluation of steroid-induced glaucoma.
1Glaucoma Research Facility, Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Eye (London, England)
|July 11, 2006
Summary
Steroid-induced glaucoma management shows that most patients achieve intraocular pressure (IOP) control with medication. However, younger patients with higher IOP and optic nerve damage may require surgery.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Pharmacological Treatments
Background:
- Steroid-induced glaucoma is a significant concern, often linked to topical steroid use.
- Elevated intraocular pressure (IOP) and optic neuropathy are key indicators.
Purpose of the Study:
- To assess intraocular pressure (IOP) control after discontinuing steroid use in patients with steroid-induced glaucoma.
- To determine the efficacy of medical versus surgical interventions for managing this condition.
Main Methods:
- Prospective evaluation of 34 patients with steroid-induced glaucoma over 18 months.
- Monitoring IOP, visual acuity, and optic disc status after steroid cessation.
- Comparing outcomes for patients treated with medication versus those requiring surgery.
Main Results:
- Topical steroid use was the primary cause of glaucoma in 73.5% of cases.
- 73.5% of patients achieved IOP control with topical medications; 26.5% required surgery.
- Patients needing surgery had significantly higher baseline IOP and vertical cup-disc ratios.
- All patients were off treatment by 18 months post-steroid cessation.
Conclusions:
- Younger patients (
- Cessation of steroid therapy allows for eventual discontinuation of treatment in all steroid-induced glaucoma cases within 18 months.