Related Experiment Videos
Prospective, long-term evaluation of steroid-induced glaucoma
1Glaucoma Research Facility, Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Eye (London, England)
|July 11, 2006
Summary
Steroid-induced glaucoma management shows that most patients achieve intraocular pressure (IOP) control with medication. However, younger patients with higher IOP and optic nerve damage may require surgery.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Pharmacological Treatments
Background:
- Steroid-induced glaucoma is a significant concern, often linked to topical steroid use.
- Elevated intraocular pressure (IOP) and optic neuropathy are key indicators.
Purpose of the Study:
- To assess intraocular pressure (IOP) control after discontinuing steroid use in patients with steroid-induced glaucoma.
- To determine the efficacy of medical versus surgical interventions for managing this condition.
Main Methods:
- Prospective evaluation of 34 patients with steroid-induced glaucoma over 18 months.
- Monitoring IOP, visual acuity, and optic disc status after steroid cessation.
- Comparing outcomes for patients treated with medication versus those requiring surgery.
Main Results:
- Topical steroid use was the primary cause of glaucoma in 73.5% of cases.
- 73.5% of patients achieved IOP control with topical medications; 26.5% required surgery.
- Patients needing surgery had significantly higher baseline IOP and vertical cup-disc ratios.
- All patients were off treatment by 18 months post-steroid cessation.
Conclusions:
- Younger patients (
- Cessation of steroid therapy allows for eventual discontinuation of treatment in all steroid-induced glaucoma cases within 18 months.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...