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Updated: Aug 7, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Metabolomic approaches to phenotype characterization and applications to complex diseases
Matej Oresic1, Antonio Vidal-Puig, Virve Hänninen
1VTT Technical Research Centre of Finland, Tietotie 2, Espoo, FIN-02044 VTT, Finland. matej.oresic@vtt.fi
Abstract:
Metabolites are the key regulators of systems homeostasis. As such, concentration changes of specific groups of metabolites may reflect systemic responses to environmental, therapeutic or genetic interventions. Thus, the study of metabolites is a powerful tool for the characterization of complex phenotypes as well as for the development of biomarkers for specific physiological responses. Therefore, metabolomics is a valuable platform for studies of complex diseases and the development of new therapies, both in nonclinical disease model characterization and clinical settings.
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