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Elevated amylase in childhood.

Alan J Howieson¹, Gordon A Mackinlay

¹Department of Paediatric Surgery, Royal Hospital for Sick Children, Sciennes Road, Edinburgh, UK. alanjhowieson@hotmail.com

Annals of Clinical Biochemistry

|July 11, 2006

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A pediatric patient presented with acute abdomen and high serum amylase. Subsequent observation revealed an inflamed parotid gland, suggesting a rare cause of elevated amylase in children.

Area of Science:

Pediatric Gastroenterology
Clinical Biochemistry

Background:

Acute abdomen in children is a common presentation requiring prompt diagnosis.
Elevated serum amylase levels can indicate various intra-abdominal pathologies.

Observation:

A 3-year-old boy presented with acute abdomen, showing benign clinical signs.
Initial investigations revealed an extremely high serum amylase titre.

Findings:

The patient was managed conservatively with observation.
An inflamed parotid gland was subsequently identified as the likely source of the elevated amylase.

Implications:

This case highlights the importance of considering parotitis as a differential diagnosis for elevated serum amylase in pediatric acute abdomen.

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Accurate diagnosis can prevent unnecessary invasive investigations and guide appropriate management.