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Non-surgical management of microperforation induced by EMR of the stomach
1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, #50 Irwon-dong, Gangnam-gu, Seoul 135-710, South Korea.
Background:
Perforation and bleeding are major complications associated with gastric endoscopic mucosal resection. Evident perforation during endoscopic mucosal resection can be managed by endoscopic clipping. However, management of microperforation is not well established.
Patient And Method:
From January 2002 to June 2004, 109 early gastric cancers and 300 adenomas were treated with endoscopic mucosal resection. Iatrogenic perforations occurred in 4.16% (n=17) patients. Following exclusion of four evident perforations, microperforation was observed in 3.18% (n=13) patients. The clinical features of microperforation in patients were retrospectively reviewed.
Results:
In a total of 13 microperforation cases, 2 patients were managed surgically. The remaining patients successfully recovered without surgical management. In the case of 11 patients without surgery, 7 experienced abdominal pain, which required analgesics, 2 patients experienced mild discomfort and 2 patients experienced no symptoms. A body temperature above 37.5 degrees C was observed in 9.1% (n=1) patients and leucocytosis above 9000 microL-1 was in 72.7% (n=8) patients. The mean duration of nasogastric tube drainage was 2.36+/-1.03 days, of fasting 4.18+/-1.17 days, of intravenous antibiotics 5.55+/-1.44 days and of hospitalisation 7.45+/-1.04 days.
Conclusion:
Microperforation induced by gastric endoscopic mucosal resection can be managed successfully using a non-surgical approach including fasting, nasogastric tube drainage and intravenous antibiotics.
Insights
Management of gastric endoscopic mucosal resection microperforations is established. Non-surgical treatment, including fasting and antibiotics, leads to successful recovery for most patients with this complication.
Area of Science:
- Gastroenterology
- Endoscopic procedures
- Surgical complications
Background:
- Gastric endoscopic mucosal resection (EMR) carries risks of perforation and bleeding.
- While evident perforations are managed with endoscopic clipping, microperforation treatment remains unclear.
Purpose of the Study:
- To review the clinical features and outcomes of microperforations following gastric EMR.
- To evaluate the efficacy of non-surgical management for gastric EMR-induced microperforations.
Main Methods:
- Retrospective review of 13 patients with microperforation after gastric EMR between January 2002 and June 2004.
- Analysis of clinical features, management strategies, and recovery outcomes.
Main Results:
- 13 cases of microperforation were identified (3.18% of EMR procedures).
- 11 out of 13 patients recovered without surgery, with symptoms including abdominal pain, mild discomfort, or no symptoms.
- Leukocytosis was observed in 72.7% of patients; non-surgical management involved nasogastric tube drainage, fasting, and intravenous antibiotics.
Conclusions:
- Gastric EMR-induced microperforation can be successfully managed non-surgically.
- Non-surgical treatment, encompassing fasting, nasogastric tube drainage, and intravenous antibiotics, is effective.
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