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Updated: Aug 7, 2026

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Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Current status of the total artificial heart
Norman A Gray1, Craig H Selzman
1Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC 27599, USA.
American Heart Journal
|July 11, 2006
Summary
Limited donor hearts make total artificial hearts crucial for advanced heart failure patients. This review covers their history, current use, and future potential in mechanical circulatory support.
Area of Science:
- Cardiology
- Biomedical Engineering
- Thoracic Surgery
Background:
- Heart transplantation is limited by donor availability, affecting advanced heart failure management.
- Mechanical circulatory support is increasingly vital for end-stage heart failure.
- Ventricular assist devices receive significant attention, but total artificial hearts are less explored.
Observation:
- Total artificial hearts represent a complete circulatory assist device.
- Recent technological advancements have enabled the deployment of various total artificial heart systems.
- This article focuses on the historical trajectory, present applications, and prospective role of total artificial hearts.
Findings:
- The historical development of total artificial hearts is reviewed.
- Current clinical applications and outcomes of total artificial hearts are discussed.
- Future directions and potential advancements in total artificial heart technology are explored.
Implications:
- Total artificial hearts offer a viable alternative for patients with limited donor options.
- Advancements in total artificial heart technology may expand treatment possibilities for heart failure.
- Understanding the evolution and future of total artificial hearts is critical for managing advanced heart failure.

