Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ischemic stroke after heart failure: a community-based study.

Brandi J Witt1, Robert D Brown, Steven J Jacobsen

  • 1Division of Cardiovascular Diseases, Mayo Clinic College of Medicine and Mayo Foundation, Rochester, MN, USA.

American Heart Journal
|July 11, 2006
PubMed
Summary

Patients with heart failure (HF) face a significantly higher risk of stroke, increasing their mortality risk by over two-fold. Stroke prevention is crucial for improving survival in HF patients, especially older individuals or those with diabetes or prior stroke.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting macrophage ferritin heavy chain mitigates ferroptosis and lung injury in experimental acute respiratory distress syndrome.

Nature communications·2026
Same author

Lessons From GBM AGILE's Regorafenib Experience in Newly Diagnosed and Recurrent Glioblastoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Less Isn't Simple: Insights From Postmastectomy Radiotherapy Deintensification Trials.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST).

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

Distinct Sarcoma Microenvironments Predict Benefit from Addition of Pembrolizumab to Preoperative Radiotherapy and Surgery in SU2C-SARC032.

medRxiv : the preprint server for health sciences·2025
Same author

Extracellular iron and the lung microbiome in smoking and COPD.

ERJ open research·2025

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Epidemiology

Background:

  • Heart failure (HF) studies on stroke incidence lack consistency due to varied designs.
  • The impact of stroke on heart failure mortality remains unclear.

Purpose of the Study:

  • To determine the incidence and risk of stroke in patients with heart failure.
  • To assess the impact of stroke on mortality in heart failure patients.

Main Methods:

  • A cohort of 630 heart failure patients (1979-1999) was identified and validated.
  • Stroke events were identified through medical record screening and physician validation.
  • Stroke risk in HF was compared to the general population using standardized morbidity ratios.

Main Results:

Related Experiment Videos

  • 16% of HF patients experienced ischemic stroke during follow-up.
  • Heart failure patients had a 17.4-fold increased stroke risk within 30 days, persisting for 5 years.
  • Stroke post-HF diagnosis increased mortality risk by 2.31 times.

Conclusions:

  • Heart failure significantly elevates ischemic stroke risk compared to the general population.
  • Stroke is associated with a substantial increase in mortality among heart failure patients.
  • Stroke prevention strategies may improve survival in heart failure, particularly for high-risk subgroups.