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Calcium absorption is not increased by caseinophosphopeptides.

Birgit Teucher1, Gosia Majsak-Newman, Jack R Dainty

  • 1Institute of Food Research, Norwich, United Kingdom.

The American Journal of Clinical Nutrition
|July 11, 2006
PubMed
Summary

Caseinophosphopeptides (CPPs) did not significantly enhance calcium absorption from functional foods. While total calcium intake increased, fractional absorption slightly decreased, indicating CPPs are unsuitable for improving calcium nutrition.

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Area of Science:

  • Nutritional Science
  • Biochemistry
  • Food Science

Background:

  • Caseinophosphopeptides (CPPs) are hypothesized to improve calcium absorption by resisting digestion and maintaining calcium solubility.
  • This property suggests potential benefits for calcium bioavailability in functional foods.

Purpose of the Study:

  • To evaluate the effect of CPP-enriched preparations on calcium absorption from a calcium lactate drink.
  • To determine the suitability of CPPs as functional food ingredients for enhancing calcium nutrition.

Main Methods:

  • A randomized crossover trial involving 15 adults.
  • Calcium absorption was measured using a dual-label calcium stable-isotope technique.
  • Participants consumed three drinks: calcium lactate alone (A) and two CPP-enriched preparations (B and C).

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Main Results:

  • Total calcium absorbed was higher from CPP-enriched drinks (B and C) compared to the control (A).
  • However, fractional calcium absorption was significantly lower from CPP-enriched drinks.
  • The CPP preparations contributed additional calcium, impacting the interpretation of fractional absorption.

Conclusions:

  • The observed differences in calcium absorption are not biologically significant.
  • Caseinophosphopeptides are not suitable as functional food ingredients for improving calcium nutrition.