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Updated: Aug 7, 2026

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
Published on: June 8, 2014
[The successful development of bisphosphonates in the therapy of osteoporosis]
Walter Josef Fassbender1, Ulla Cordula Stumpf, Andreas Kurth
1Hospital zum Hl. Geist Kempen, Akademisches Lehrkrankenhaus der Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany. w.j.fassbender@krankenhaus-kempen.de
Abstract:
In the last 30 years bisphosphonates have been used in the treatment of different bone diseases. Bisphosphonates in their oral pharmaceutical form are an established and approved medication in osteoporosis treatment for years. Latest research developed more potent bisphosphonates in different application forms: oral and parenteral. Therefore, their prospects for medical treatment could be enlarged to the fields of oncology, hematology, and osteology. Bisphosphonates are innovative in case of adjuvant therapy as well as in adequate pain therapy. In the medical treatment of osteoporosis and metabolic osteopathies bisphosphonates could be rightly denoted as groundbreaking.
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