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Thyroid function in depression.

Kajal Chakrabarti1, Pradip Man Singh, Suraj Prasad Joshi

  • 1Department, of Psychiatry, Nepal Medical College, Teaching Hospital Jorpati, Kathmandu.

Nepal Medical College Journal : NMCJ
|July 11, 2006
PubMed
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Depression is linked to thyroid dysfunction. This study found that patients with depression often have lower T3 and T4 levels and higher Thyroid Stimulating Hormone (TSH), indicating sub-hypothyroidism.

Area of Science:

  • Endocrinology
  • Psychiatry
  • Metabolic research

Background:

  • Thyroid hormones play a crucial role in regulating mood and cognitive functions.
  • Alterations in thyroid function have been observed in various psychiatric disorders, including depression.

Purpose of the Study:

  • To investigate the thyroid function in patients diagnosed with depression.
  • To determine the prevalence of thyroid dysfunction, specifically sub-hypothyroidism, in a cohort of depressive patients.

Main Methods:

  • Thyroid function tests were conducted on 34 patients presenting with depression.
  • Key thyroid hormones measured included T3, T4, and Thyroid Stimulating Hormone (TSH).

Main Results:

  • Patients with depression exhibited diminished levels of triiodothyronine (T3) and thyroxine (T4).

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  • A concurrent increase in Thyroid Stimulating Hormone (TSH) levels was observed in the depressive patient group.

    • Conclusions:

    • The findings suggest a significant association between depression and thyroid dysfunction.
    • Depressive patients in this study frequently presented with sub-clinical hypothyroidism, highlighting the importance of thyroid screening in depression management.