Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[HIV-2 in The Netherlands].

G J van Doornum1, R van den Akker, J Buitenwerf

  • 1Rijksinstituut Voor Volksgezondheid en Milieuhygiëne, Laboratorium voor Virologie, Bilthoven.

Nederlands Tijdschrift Voor Geneeskunde
|November 9, 1991
PubMed
Summary

In the Netherlands before February 1991, at least 18 cases of Human Immunodeficiency Virus type 2 (HIV-2) infection were identified. Combined HIV-1/2 testing is crucial for Dutch laboratories to detect HIV-2, especially in individuals with links to specific regions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantification of viral DNA and liver enzymes in plasma improves early diagnosis and management of herpes simplex virus hepatitis.

Journal of viral hepatitis·2010
Same author

Multiple surface antigen mutations in five blood donors with occult hepatitis B virus infection.

Journal of medical virology·2008
Same author

Severe influenza resembling hemorrhagic shock and encephalopathy syndrome.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2007
Same author

Quantitative detection of herpes simplex virus DNA in the lower respiratory tract.

Journal of medical virology·2007
Same author

Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cancer.

European urology·2005
Same author

[From fowl plague to influenza pandemic; a reason for taking precaution].

Nederlands tijdschrift voor geneeskunde·2004

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Context:

  • Prior to February 1991, Human Immunodeficiency Virus type 2 (HIV-2) infections were identified in the Netherlands.
  • The epidemiological profile of HIV-2 cases differed significantly from that of HIV-1 in the Netherlands.
  • Most identified HIV-2 cases were linked to sub-Saharan Africa or the Cape Verdean Islands, with a predominantly heterosexual transmission pattern.

Purpose:

  • To report the incidence of HIV-2 infections in the Netherlands.
  • To recommend appropriate diagnostic strategies for HIV-2 detection.
  • To highlight the distinct epidemiological characteristics of HIV-2 compared to HIV-1.

Summary:

  • Data from HIV confirmation laboratories revealed at least 18 cases of HIV-2 infection in the Netherlands before February 1991.

Related Experiment Videos

  • Diagnostic interpretation involves combined HIV-1/2-ELISA, specific HIV-1-ELISA, and HIV-1 western immunoblot patterns.
  • Confirmation requires western blots of HIV-1 and HIV-2 viral lysates and transmembranous region peptide tests.
  • The majority of HIV-2 cases involved heterosexual transmission, with 13 of 18 infected individuals being women, contrasting with HIV-1 epidemiology.

    • Impact:

    • Urgent recommendation for the implementation of combined HIV-1/2 tests in Dutch diagnostic and blood bank laboratories.
    • Highlights the need for vigilance regarding potential further spread of HIV-2 through heterosexual contact in the Netherlands.
    • Informs public health strategies for managing and preventing HIV-2 transmission.