Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Cushing's syndrome.

Amal Shibli-Rahhal¹, Marta Van Beek, Janet A Schlechte

¹Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

Clinics in Dermatology

|July 11, 2006

Summary

Cushing's syndrome, caused by excess glucocorticoids, leads to metabolic and skin issues. Screening tests like 24-hour urine cortisol help diagnose this condition, guiding further endocrinologist evaluation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Restorative Community Building Practices: A Train-the-Trainer Workshop for Medical Students, Staff, and Faculty.

MedEdPORTAL : the journal of teaching and learning resources·2025

Same author

Restorative Justice Practices as a Foundation for Medical Education Innovation.

The clinical teacher·2024

Same author

Ultra-low dose hip CT-based automated measurement of volumetric bone mineral density at proximal femoral subregions.

Medical physics·2024

Same author

National Survey of the Bone Densitometry Evaluation Process Within an Integrated Healthcare System.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry·2023

Same author

Association between RAAS Antagonism and COVID-19-related Mortality in Patients with Overweight/Obesity-related Hypertension: A Retrospective Cohort Study.

Arquivos brasileiros de cardiologia·2023

Same author

The 2022 Annual Report of DataDerm: The database of the American Academy of Dermatology.

Journal of the American Academy of Dermatology·2023

Area of Science:

Endocrinology
Internal Medicine

Background:

Cushing's syndrome arises from prolonged exposure to excess glucocorticoids.
It manifests with diverse metabolic complications such as obesity, hyperglycemia, and hypertension.
Dermatological signs include skin atrophy, bruising, and hirsutism.

Purpose of the Study:

To outline the clinical presentation of Cushing's syndrome.
To detail the diagnostic screening methods for hypercortisolism.

Main Methods:

Review of clinical features associated with excess glucocorticoids.
Description of standard screening tests: 24-hour urine cortisol, dexamethasone suppression test, and late-night salivary cortisol.

Main Results:

Abnormal screening tests necessitate further endocrine evaluation.
Normal screening results effectively rule out Cushing's syndrome.

Conclusions:

Early identification of Cushing's syndrome is crucial for managing associated health problems.
Screening tests play a vital role in diagnosing hypercortisolism and directing patient care.

Related Experiment Videos