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Updated: Aug 7, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Adverse outcome in women with thrombophilia and bilateral uterine artery notches
Elvira Grandone1, Donatella Colaizzo, Pasquale Martinelli
1IRCCS Casa Sollievo della Sofferenza, S. Giovanni R. (FOGGIA), Foggia, Italy. e.grandone@operapadrepio.it
Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher risk to have an adverse outcome than women without.
Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher risk to have an adverse outcome than women without.
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