Related Experiment Video
Updated: Aug 7, 2026
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Nipple sparing subcutaneous mastectomy: sixty-six months follow-up
F Caruso1, M Ferrara, G Castiglione
1Department of Surgical Oncology, Humanitas Centro Catanese di Oncologia, Via Dabormida 64, 95100 Catania, Italy.
Aim:
Validation of oncological and reconstructive efficacy of nipple sparing subcutaneous mastectomy.
Methods:
We enrolled 50 patients on behalf of Humanitas Centro Catanese di Oncologia fulfilling appropriate reconstructive and oncological criteria to undergo nipple sparing subcutaneous mastectomy. We preferably selected women with medium size-small breast affected by early stage breast cancer peripherally located with intra-operative negative frozen section of the major ducts.
Results:
fourty-six patients were alive after a mean follow-up of 5.5 years. We observed a single case of local recurrence in the nipple successfully treated with local excision. Five patients presented metastatic disease. One is currently alive, 4 died because of progressive disease.
Conclusions:
Our study supports other findings regarding safety and efficacy of nipple sparing subcutaneous mastectomy for selected patients.
