Related Experiment Video
Updated: Aug 7, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Urinary-catheter-associated infections in the elderly
1Department of Internal Medicine, Ohio State University, Columbus, OH, USA. ckunin@columbus.rr.com
Abstract:
The indwelling urinary catheter is the leading cause of complicated urinary tract infections and Gram-negative bacteraemia in this age group. It accounts for about 40% of life-threatening septicaemia. There is a progressive increase in mortality independently associated with the duration of catheterization. Polymicrobial bacteriuria is common. Urease-producing bacteria lead to encrusted and blocked catheters. The current challenges are to develop effective methods to sensitize healthcare workers to avoid the routine use of indwelling catheters, remove them when no longer needed, develop alternative methods for care of incontinence, employ non-invasive methods to measure urine output, and improve urine drainage systems. The research paradigm needs to focus on prevention of catheter-associated infections rather than on futile attempts to treat irreversible sepsis.
Related Concept Videos
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection I: Introduction
Urinary Tract Infection IV: Nursing Management
Urine Studies II: Urine Culture and Sensitivity Test
Nursing Assessment of the Genitourinary System I: Health History
