Influence of intravenous hyperalimentation on cardiac dimensions and heart function

Eleven severe malnourished patients, mean age 34 yrs and mean weight 66 per cent of ideal body weight, were studied to evaluate the effect of intravenous hyperalimentation on the function and size of the heart. Left ventricular size and systolic function were measured before and after a mean weight gain of 19 per cent with electro, vector, echo and phonomechanographic methods. During hyperalimentation a statistically significant increase in left ventricular mass (p<0.01) was observed. Correction for body weight showed a parallel increase between the parameters and weight gain. Echocardiographic and phonomechanographic indexes of left ventricular systolic function remained unchanged. A decrease of the amplitude of the maximal spatial QRS vector was shown by vectocardiography. These results indicate that during intravenous hyperalimentation of the severe malnourished a proportional increase in cardiac size and mass occurs with preservation of the left ventricular systolic function.