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[Khat, a herbal drug with amphetamine properties].
P Kalix1, R Brenneisen, U Koelbing
1Psychiatrische Universitäts-Poliklinik, Bern.
Summary
Khat leaves, containing the stimulant cathinone, are chewed for their amphetamine-like effects. This article details the pharmacology of khat, a practice spreading globally.
Area of Science:
- Pharmacology
- Ethnobotany
- Drug Science
Context:
- Khat (Catha edulis) is a stimulant plant traditionally consumed in East Africa and Yemen.
- The practice of chewing khat is increasing globally, necessitating medical awareness.
- Fresh khat leaves contain active compounds, primarily cathinone.
Purpose:
- To inform medical practitioners about the effects and pharmacology of khat.
- To review current scientific understanding of khat's constituents and actions.
- To address the growing international presence of khat use.
Summary:
- Khat contains cathinone, a natural amphetamine responsible for its stimulant effects.
- Pharmacological research has identified cathinone as the principal active alkaloid in khat.
- The article synthesizes current knowledge on khat's pharmacology.
Impact:
- Enhances clinical understanding of khat's stimulant properties.
- Provides essential information for healthcare providers managing khat use.
- Supports public health initiatives by detailing the pharmacology of a spreading psychoactive substance.