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Published on: June 16, 2020
[HAQ-DI Italian version in systemic sclerosis]
G La Montagna1, G Cuomo, I Chiarolanza
1Dipartimento di Internistica Clinica e Sperimentale F. Magrassi e A. Lanzara, Seconda Università degli Studi di Napoli, Sezione di Reumatologia.
Insights
The Italian version of the Health Assessment Questionnaire Disability Index (HAQ-DI) is a valid tool for assessing disability in systemic sclerosis (SSc) patients. Higher HAQ-DI scores correlated significantly with skin sclerosis, joint contractures, myopathy, and digital ulcers.
Area of Science:
- Rheumatology
- Clinical Assessment
- Systemic Sclerosis Research
Background:
- Systemic sclerosis (SSc) is a complex autoimmune disease affecting the skin and internal organs.
- Accurate disability assessment is crucial for managing SSc patients.
- The Health Assessment Questionnaire Disability Index (HAQ-DI) is a widely used tool, but its Italian version requires validation in SSc.
Purpose of the Study:
- To investigate the validity and reliability of the Italian version of the HAQ-DI in patients with systemic sclerosis.
- To explore the correlation between HAQ-DI scores and specific SSc disease manifestations.
Main Methods:
- 121 SSc patients meeting ACR criteria were enrolled.
- The Italian version of HAQ-DI, previously validated for rheumatoid arthritis, was administered.
- Associations between HAQ-DI scores and disease subset, skin sclerosis extent, joint contractures, myopathy, and digital ulcers were analyzed.
Main Results:
- The mean HAQ-DI score for SSc patients was 0.772 ± 0.074.
- Statistically significant differences in HAQ-DI scores were observed between patients with and without wide skin sclerosis (P<0.001).
- Higher HAQ-DI scores were significantly associated with joint contractures (P<0.001), myopathy (P<0.001), and digital ulcers (P=0.006).
Conclusions:
- The findings support the validity of the Italian version of HAQ-DI for assessing disability in systemic sclerosis.
- The HAQ-DI effectively captures disability related to key SSc complications.
- This validated tool can aid in the clinical management and research of SSc in Italy.
Objective:
To investigate the Italian version of HAQ-DI (Health Assessment Questionnaire Disability Index) in systemic sclerosis (SSc).
Methods:
121 SSc patients, satisfying ACR criteria for the classification of this disease and consecutively admitted to a tertiary Unit, were invited to participate to the study. The Italian version of HAQ-DI, as validated in rheumatoid arthritis, was administered to each of them. The relationships between this parameter and the following disease aspects: disease subset, wide extent of skin sclerosis, joint contractures, myopathy, active digital ulcers, were investigated.
Results:
HAQ-DI resulted to be 0.772+/-0.074 (mean+/-SE) Statistically significant differences in HAQ-DI scores were detected between patients with and respectively without wide extent of skin sclerosis (ie modified Rodnan skin score >14) (1.158+/-0.176 vs 0.652+/-0.076; P<0.001), joints contractures (0.839+/-0.076 vs 0.159+/-0.147; P<0.001), myopathy (1.875+/-0.184 vs 0.656+/-0.071; P<0.001), digital ulcers (1.047+/-0.135 vs 0.680+/-0.109; P=0.006).
Conclusions:
Our data support the validity of the Italian version of HAQ-DI in SSc.
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