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Published on: September 12, 2020
Impact of bilateral pallidal stimulation on DYT1-generalized dystonia in Japanese patients
Satoshi Goto1, Kazumichi Yamada, Hideki Shimazu
1Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan. sgoto@kaiju.medic.kumamoto-u.ac.jp
Abstract:
Early-onset generalized dystonia attributable to a DYT1 gene mutation is a hyperkinetic movement disorder that responds poorly to pharmacotherapy. In this video brief, we show that continuous bilateral stimulation of the globus pallidus internus produced sustained and marked improvements in the motor symptoms and functional disabilities of Japanese patients with DYT1-generalized dystonia.
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