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Correlation between brachial-ankle pulse wave velocity and arterial compliance and cardiovascular risk factors in

Baoying Li1, Haiqing Gao, Xiaoli Li

  • 1Department of Geriatrics, Qi-Lu Hospital of Shandong University, Jinan, PR China.

Hypertension Research : Official Journal of the Japanese Society of Hypertension
|July 13, 2006
PubMed

Insights

This study shows that brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI) effectively identify vascular damage in elderly patients with arteriosclerosis. These measures correlate with key cardiovascular risk factors, highlighting their clinical utility.

Area of Science:

  • Cardiovascular Medicine
  • Gerontology
  • Vascular Biology

Background:

  • Arteriosclerosis is a significant health concern in the elderly population.
  • Assessing vascular damage is crucial for managing cardiovascular risk.
  • Established markers for vascular stiffness and function need validation in this demographic.

Purpose of the Study:

  • To investigate the association between major cardiovascular risk factors and specific measures of arterial stiffness and compliance.
  • To evaluate the utility of brachial-ankle pulse wave velocity (baPWV), ankle-brachial index (ABI), capacitive arterial compliance (C1), and oscillatory arterial compliance (C2) in elderly arteriosclerosis patients.

Main Methods:

  • Analysis of 160 elderly patients diagnosed with arteriosclerosis.
  • Assessment of vessel wall properties using baPWV and ABI via a VP-1000 system.
  • Measurement of arterial compliance (C1 and C2) using a DO-2020 Cardiovascular Profiling Instrument.
  • Application of multiple regression analysis to determine correlations.

Main Results:

  • baPWV demonstrated significant correlations with systolic blood pressure, mean artery pressure, pulse pressure, diastolic blood pressure, age, and heart rate.
  • ABI showed significant correlations with pulse pressure, systolic blood pressure, and age.
  • C1 correlated significantly with pulse pressure, systolic blood pressure, mean artery pressure, age, diastolic blood pressure, and heart rate.
  • C2 was significantly correlated with age, systolic blood pressure, pulse pressure, diastolic blood pressure, fasting blood glucose, mean artery pressure, and heart rate.
  • No strong correlations were found between baPWV, ABI, or C1 and body mass index, total cholesterol, or triglycerides.
  • Significant correlations were observed between baPWV and C1, and between baPWV and C2.

Conclusions:

  • baPWV and ABI are effective tools for identifying vascular damage in aged individuals.
  • These non-invasive measures provide valuable insights into the arterial health of elderly patients with arteriosclerosis.
  • The study reinforces the clinical relevance of baPWV and ABI in cardiovascular risk assessment.

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