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[Allergic rhinitis: A challenge diagnosis].

N Fuiano1, D A Procaccini, A Pietrobelli

  • 1Unità di Allergologia Pediatrica, A. USL Fg 1, San Severo, Foggia, Italy. fuiano50@tin.it

Minerva Pediatrica
|July 13, 2006
PubMed
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Diagnosing allergic rhinitis is challenging, as skin prick tests and nasal specific IgE tests showed limited correlation with symptoms. Family history and clinical signs remain crucial for accurate diagnosis.

Area of Science:

  • Allergology
  • Immunology
  • Pediatrics

Background:

  • Allergic rhinitis is a common condition, affecting 10-25% of the general population and significant percentages of children and adolescents.
  • Diagnosis relies on family history, symptoms, and specific IgE testing, including skin prick tests and nasal IgE measurements.
  • Current diagnostic methods for allergic rhinitis require further refinement for improved accuracy.

Purpose of the Study:

  • To evaluate the relationship between positive skin prick tests and nasal specific IgE levels in patients with rhinitis.
  • To assess the correlation between allergic rhinitis diagnostic tests and patient symptoms, gender, and age.
  • To compare the diagnostic efficacy of skin prick tests versus nasal specific IgE measurements.

Main Methods:

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  • A cohort of 125 subjects (48-216 months) underwent both skin prick testing and nasal specific IgE testing.
  • Data analysis focused on the concordance between the two tests and their relationship with clinical presentation.
  • Subjects were consecutively enrolled for the study.

    • Main Results:

    • Out of 125 subjects, 51 tested positive for both skin prick and nasal specific IgE.
    • 23 subjects were positive only to skin prick tests, while 31 were positive only to nasal specific IgE.
    • No significant correlation was found between positive test results and the presence of rhinitis symptoms.

    Conclusions:

    • The diagnosis of allergic rhinitis presents significant challenges, indicating a need for more precise and accurate diagnostic tools.
    • Skin prick tests and nasal specific IgE tests demonstrated limited correlation with symptoms in this study cohort.
    • Family history and clinical evaluation remain fundamental components in the accurate diagnosis of allergic rhinitis.