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Mumps in a boarding school: description of an outbreak and control measures
Douglas G Mackenzie1, George Craig, Nicholas F Hallam
1Public Health Department, NHS Fife, Cameron House, Windygates, Leven, Fife KY8 5RG. gm@nhs.net
Background:
The number of cases of mumps in the UK has increased during 2004-2005. Understanding why some people are more susceptible to mumps infection will help target vaccination and other control measures in the future. This paper describes a mumps outbreak in a boarding school in Scotland (October to November 2004).
Objectives:
To describe the characteristics of cases in a mumps outbreak; and to conduct a case-control study looking at the effect of previous measles-mumps-rubella (MMR) vaccination.
Design:
Descriptive epidemiology.
Data Sources:
Clinical, laboratory and surveillance data.
Setting:
A private school with 600 boarding and day pupils.
Results:
Fifty cases were notified to the public health department as having mumps. Twenty of the cases (40%) were confirmed virologically, all born between 1987-1991. A matched case-control study was conducted to explore the effect of prior MMR vaccination. Compared to no vaccine, MMR protected against mumps (odds ratio = 0.7), two doses offering best protection (odds ratio = 0.5), but the study was not large enough to detect a statistically significant difference.
Conclusion:
Some children and young people in the UK are currently incompletely vaccinated. This outbreak illustrates the potential of a mumps outbreak to disrupt the medical, educational and social life of a school. All children should be vaccinated with two doses of MMR vaccine before school entry. Children and young people born between 1979-1991 should be given the necessary additional dose(s) of MMR vaccine.
Insights
Mumps outbreaks can disrupt school life, highlighting the need for complete vaccination. Two doses of the measles-mumps-rubella (MMR) vaccine offer the best protection against mumps infection.
Area of Science:
- Epidemiology
- Public Health
- Vaccinology
Background:
- The UK experienced a rise in mumps cases during 2004-2005.
- Understanding mumps susceptibility is crucial for effective control strategies.
- A mumps outbreak occurred in a Scottish boarding school from October to November 2004.
Purpose of the Study:
- To characterize cases during a mumps outbreak.
- To investigate the impact of prior measles-mumps-rubella (MMR) vaccination through a case-control study.
Main Methods:
- Descriptive epidemiological analysis.
- Utilized clinical, laboratory, and surveillance data.
- Conducted a matched case-control study within a private boarding school of 600 pupils.
Main Results:
- Fifty mumps cases were reported, with 40% confirmed virologically.
- Cases were predominantly individuals born between 1987-1991.
- MMR vaccination showed a protective effect (OR=0.7), with two doses offering the best protection (OR=0.5), though not statistically significant due to study size.
Conclusions:
- Incomplete vaccination leaves some children and young people vulnerable to mumps.
- Mumps outbreaks can significantly disrupt school operations and student life.
- Recommends two MMR vaccine doses before school entry and additional doses for those born between 1979-1991.
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