Neuregulin effect on quantal content dissociated from effect on miniature endplate potential amplitude

Mary Anne Mann1, Saumya Das, Jinghua Zhang

  • 1Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. mam2012@columbia.edu

Summary

Neuregulin signaling impacts acetylcholine receptor (AChR) function. In NRG-deficient mice, changes in AChR density and transmitter release occur at different developmental times, affecting muscle maturation.