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Symptomatic bradycardia caused by mianserin at therapeutic doses
B Carcone1, T Vial, N Chaillet
1Service de Médecine, Hôtel Dieu, Le Creusot, France.
Human & Experimental Toxicology
|September 1, 1991
Abstract:
An acute episode of symptomatic sinus bradycardia, occurred in a 50-year-old female patient after she had been given a single therapeutic dose of mianserin. Heart rate was corrected by atropine injection. Re-administration of mianserin resulted in the recurrence of bradycardia. Further examination showed no cardiac abnormalities. This case is the first report of conduction defect in a patient given therapeutic doses of mianserin.