Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Egg allergy].

C Alessandri1, M Calvani

  • 1Divisione Pediatrica, Ambulatorio Allergologico, Ospedale S. Camillo de Lellis, Roma, Italy. claudia.alessandri@fastwebnet.it

Minerva Pediatrica
|July 13, 2006
PubMed
Summary
This summary is machine-generated.

Egg allergy is a common childhood food allergen. Diagnosis relies primarily on clinical evaluation and double-blind placebo-controlled food challenges, with dietary elimination as the primary treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Role of FGF7 in Tumor-Induced Osteomalacia. Clinic-Pathologic Analysis in a Patient with a Sino-Nasal Phosphaturic Mesenchymal Tumor.

Calcified tissue international·2025
Same author

Cryptogenic stroke and seronegative antiphospholipid syndrome: a case series of patients with positivity for "non-criteria" antiphospholipid antibodies.

Reumatismo·2024
Same author

Retention rate of abatacept in rheumatoid arthritis patients in a real-life setting: results from a monocentric cohort.

Reumatismo·2024
Same author

Patients with systemic lupus erythematosus and their experience with vaccination against COVID-19: a descriptive and explanatory study.

Reumatismo·2022
Same author

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients.

Frontiers in pharmacology·2022
Same author

Immune checkpoint inhibitors and pre-existing antinuclear antibodies: the rheumatologist point of view.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same journal

Developmental and behavioral profile in a domestic adoptees sample: a new challenge for the pediatrician.

Minerva pediatrica·2020
Same journal

A new approach to the diagnosis of short stature.

Minerva pediatrica·2020
Same journal

Management of the main endocrine and diabetic disorders in children.

Minerva pediatrica·2020
Same journal

Kounis Syndrome: a pediatric perspective.

Minerva pediatrica·2020
Same journal

Human inborn errors of immunity caused by defects of receptor and proteins of cellular membrane.

Minerva pediatrica·2020
Same journal

Tall stature in children and adolescents.

Minerva pediatrica·2020
See all related articles

Area of Science:

  • Pediatric Allergy and Immunology
  • Clinical Nutrition
  • Immunopathology

Context:

  • Egg allergy is a significant concern in pediatric nutrition and feeding.
  • Immediate, type I, IgE-mediated hypersensitivity is the primary pathogenic mechanism, though other pathways exist.
  • Sensitization can occur prenatally or via breast milk, particularly in infants with atopic dermatitis.

Purpose:

  • To review the diagnostic approaches and management strategies for egg protein allergy in children.
  • To emphasize the clinical basis of diagnosis and the role of double-blind placebo-controlled food challenges (DBPCFC) as the gold standard.
  • To discuss the limitations of skin prick tests and specific IgE (sIgE) values for individual diagnosis.

Summary:

  • Clinical assessment and DBPCFC are the cornerstones for diagnosing egg allergy.

Related Experiment Videos

  • While prick tests and sIgE offer group-level predictive value, they lack individual diagnostic accuracy, especially in children with atopic dermatitis.
  • Dietary elimination of hen egg is the primary management strategy, with careful consideration of cross-reactivity to other avian eggs.
  • Cross-reactivity with poultry meat is infrequent (around 5%).

    • Impact:

    • Provides clarity on the diagnostic gold standard for egg allergy, guiding clinical practice.
    • Highlights the limitations of serological and skin-based allergy tests for individual diagnosis in children.
    • Informs management by emphasizing strict dietary exclusion and addressing cross-reactivity concerns.
    • Supports the safe vaccination of egg-allergic children, including the measles-mumps-rubella (MMR) vaccine.