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Discrepancies between medication records of anticoagulation clinics and pharmacy records
Tom Schalekamp1, Carolien Smit, Johanna H H van Geest-Daalderop
1Department of Pharmacoepidemiology and Pharmacotherapy, University Institute of Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands. t.schalekamp@pharm.uu.nl
Purpose:
To determine whether there were discrepancies between with coumarin anticoagulants interacting medications recorded in medical files of anticoagulation clinics (AC-records) and computerized records of community pharmacies (pharmacy records).
Methods:
A descriptive study was conducted at two Dutch anticoagulation clinics (AC's). Records of with coumarin anticoagulants interacting drugs at the AC's were compared with the pharmacy records. A drug registered in the pharmacy records but not in the AC-records, was recorded as a discrepancy, while a drug registered in AC-records as well as in pharmacy records, was recorded as a match.
Results:
Of the 117 identified interacting drugs registered in pharmacy records 32 (27%) were not registered in the AC-records. In four out of seven patients of whom the use of a pharmacokinetically interacting drug was not registered in the AC-records, several INR-values exceeded the upper therapeutic range.
Conclusion:
This study demonstrates that a substantial percentage of drugs of which an interaction with coumarin anticoagulants can be expected, is not registered in the medical files of anticoagulation clinics.
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