Practical methodologies for the synthesis of indoles

Discovery Process of Enlicitide, a Highly Engineered Macrocyclic Peptide Therapeutic, through Issue-Driven Fragment-Based Synthetic Assembly and SAR.

Journal of medicinal chemistry·2026

Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide.

Science (New York, N.Y.)·2026

Total Synthesis of Enlicitide Decanoate.

Journal of the American Chemical Society·2025

Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.

Organic letters·2023

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.

Circulation·2023

A kinase-cGAS cascade to synthesize a therapeutic STING activator.

Nature·2022

Conformational Switching on Lipid Interfaces: Lessons from Refolding and Membrane Insertion of Diphtheria Toxin, BCL-2 Apoptotic Regulators and pHLIP.

Chemical reviews·2026

Folding and Oligomerization of CLC Channels and Transporters.

Chemical reviews·2026

Materials and Device Engineering for Efficient, Stable, and Scalable Monolithic Perovskite/Silicon Tandem Photovoltaics.

Chemical reviews·2026

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Chemical reviews·2026

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026

Palladium-catalyzed asymmetric dearomative (3+2) annulation toward skeletally diverse spirocyclohexadienones.

Chemical communications (Cambridge, England)·2026

Enantioconvergent access to 1,1-diarylmethine silanes and germanes through nickel/photoredox-catalyzed cross-electrophile coupling.

Chemical science·2026

A radical-polar crossover approach to complex nitrogen heterocycles via the triplet state.

Chem·2026

Solvent effects on the radical scavenging activity of HP-136 benzofuranone: mechanistic and kinetic insights from quantum chemical calculations.

RSC advances·2026

Flash Communication: Mechanochemical Synthesis of Magnesium Anthracenes.

Organometallics·2026

Diphenylsilylene Transfer to 2-(β-Styryl)benzofurans: Synthesis of Polycyclic Compounds Containing One, Two, or Three Silicon Atoms via Carbon Skeletal Reorganization.

Organic letters·2026

Related Experiment Videos

Practical methodologies for the synthesis of indoles

Related Concept Videos

Discovery Process of Enlicitide, a Highly Engineered Macrocyclic Peptide Therapeutic, through Issue-Driven Fragment-Based Synthetic Assembly and SAR.

Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide.

Total Synthesis of Enlicitide Decanoate.

Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.

A kinase-cGAS cascade to synthesize a therapeutic STING activator.

Conformational Switching on Lipid Interfaces: Lessons from Refolding and Membrane Insertion of Diphtheria Toxin, BCL-2 Apoptotic Regulators and pHLIP.

Folding and Oligomerization of CLC Channels and Transporters.

Materials and Device Engineering for Efficient, Stable, and Scalable Monolithic Perovskite/Silicon Tandem Photovoltaics.

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Palladium-catalyzed asymmetric dearomative (3+2) annulation toward skeletally diverse spirocyclohexadienones.

Enantioconvergent access to 1,1-diarylmethine silanes and germanes through nickel/photoredox-catalyzed cross-electrophile coupling.

A radical-polar crossover approach to complex nitrogen heterocycles via the triplet state.

Solvent effects on the radical scavenging activity of HP-136 benzofuranone: mechanistic and kinetic insights from quantum chemical calculations.

Flash Communication: Mechanochemical Synthesis of Magnesium Anthracenes.

Diphenylsilylene Transfer to 2-(β-Styryl)benzofurans: Synthesis of Polycyclic Compounds Containing One, Two, or Three Silicon Atoms via Carbon Skeletal Reorganization.

Related Experiment Videos

Practical methodologies for the synthesis of indoles

Related Concept Videos

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