Related Experiment Video
Updated: Aug 7, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Brief report: patient cognitive status and the identification and management of depression by primary care physicians
Monica K Crane1, Hillary R Bogner, Peter V Rabins
1Geriatrics Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. monica.crane@uphs.upenn.edu
Objectives:
No known study has examined the role of patients' cognitive impairment in the identification and management of depression by primary care physicians.
Design:
A cross-sectional survey conducted between 2001 and 2003.
Participants:
A sample of 330 adults aged 65 and older from Maryland primary care practices with complete information on cognitive and psychological status, and physician assessments.
Measurements:
Primary care physicians were asked to rate cognition and depression on a Likert scale, as well as report management of depression within 6 months of the index visit. Patient interviews included standardized measures of psychological and cognitive status.
Results:
Older adults identified as depressed by their physician were more likely to be identified as cognitively impaired (unadjusted odds ratio [OR] = 3.71, [95% confidence interval] [CI] [1.93, 7.16]). Older adults identified as cognitively impaired had a tendency to be managed for depression (unadjusted OR = 2.62, 95% CI [0.96, 7.19]). In adjusted multivariate models, these associations remained unchanged.
Conclusions:
When physicians identified a patient as cognitively impaired, they were more likely to identify the patient as depressed and to report treatment of the depression. An understanding of how physicians think about depression in the context of cognitive impairment is important for designing depression interventions for older adults.
Related Concept Videos
Depression: Overview
Cognitive Therapy
Acute Coronary Syndrome IV: Interprofessional Care
Antidepressant Drugs: Overview
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Antidepressant Drugs: MAOIs and Other Agents

