HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample

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Published on: November 3, 2023

Roel G W Verhaak1, Mathijs A Sanders, Maarten A Bijl

  • 1Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands. r.verhaak@erasmusmc.nl

BMC Bioinformatics
|July 14, 2006
PubMed
Abstract

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...