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A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Home parenteral nutrition in children: 8 years of experience with 112 patients

C Ricour1, A M Gorski, O Goulet

  • 1Centre of home parenteral nutrition, Hôpital des Enfants-Malades, 149, rue de Sèvres, 75743 Paris, France.

Clinical Nutrition (Edinburgh, Scotland)
|April 1, 1990
PubMed

Insights

Home parenteral nutrition (HPN) allows children with intestinal failure to achieve a good quality of life. This high-tech treatment requires specialized centers for successful long-term management.

Area of Science:

  • Pediatric Gastroenterology
  • Intestinal Rehabilitation
  • Home Healthcare

Background:

  • Children with anatomical or functional loss of the small bowel often require prolonged parenteral nutrition.
  • Maintaining a normal quality of life and enabling home discharge are crucial for these children's well-being.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of home parenteral nutrition (HPN) in children requiring long-term nutritional support.
  • To assess the impact of HPN on growth, quality of life, and complications in pediatric patients.

Main Methods:

  • A retrospective review of 112 children on cyclic HPN over 8 years.
  • Analysis of patient outcomes including HPN status, growth, quality of life, and complications.

Main Results:

  • 49 children were successfully weaned off HPN, while 45 remained on HPN.
  • Growth and quality of life were generally good, with a low rate of severe infection (1 sepsis per 594 days on HPN).
  • 18 children died during the study period.

Conclusions:

  • Home parenteral nutrition is a viable and effective option for children needing prolonged nutritional support.
  • Successful HPN requires management within a specialized center offering comprehensive patient follow-up and logistical support.
  • HPN significantly improves quality of life for pediatric patients with intestinal failure.

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