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The effect of parenteral nutrition with different lipid emulsions on platelets
1Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin, New Zealand.
Abstract:
This study investigated the effect of parenteral nutrition including 500 ml/day of two different lipid emulsions on platelet numbers and platelet aggregation. One lipid contained 20% long chain triglycerides, the other a mixture of 10% medium chain triglycerides and 10% long chain triglycerides. After 7-10 days parenteral feeding, platelet numbers had not changed significantly, platelet morphology appeared normal and the prothrombin time was unaltered. Platelet aggregation in response to varying concentrations of ADP, adrenaline and collagen was not significantly different from pre-feeding and was similar in patients receiving the two different lipids.
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