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Published on: June 14, 2019
Histopathological and immunohistochemical aspects in both basaloid and spindle cell variant of cervical carcinoma
Daniela Drîgnei-Veselu1, Cristiana Simionescu, Claudia Valentina Georgescu
1Department of Anatomic Pathology, "Victor Babeş" Hospital of Infectious Diseases and Pneumopathology, Craiova. dana_drignei@yahoo.com
Abstract:
The study was performed by using a number of eight cases of cervical carcinomas suiting to basaloid carcinomas and spindle cell carcinomas under the circumstances of usual histopathological staining. Immunohistochemically we used anticytokeratin monoclonal antibody (AE1/AE3) to confirm the epithelial differentiation and also PCNA to evaluate the cell proliferation rate. Tumor positiveness for AE1/AE3 cytokeratin cocktail confirmed its epithelial nature. Immunoexpression for PCNA indicated a high index of cell proliferation for all the cases with a more increased value for the basaloid carcinomas.

