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Effect of the thiol group on experimental gold-induced autoimmunity
H Tournade1, J C Guery, R Pasquier
1INSERM U28, Department de Pathologie Rénale et Vasculaire, Hôpital Broussais, Paris, France.
Arthritis and Rheumatism
|December 1, 1991
Abstract:
Brown Norway rats injected with aurothiopropanolsulfonate sodium salt develop systemic autoimmunity. The aim of this study was to assess the influence of the sulfur-containing group in this experimental model of gold-induced autoimmunity. It was shown that the sulfur-containing group does not induce autoimmunity of itself, but potentiates the immunotoxic effects of gold.