Related Experiment Video
Updated: Aug 7, 2026
06:11
A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
Effects of corticoliberin fragment CRF(4-6) on sexual behavior in male rats [corrected]
A A Andreev-Andrievskii1, D V Tsvirkun, E Yu Makarenko
1M. V. Lomonosov Moscow State University, Vorob'evy Gory, 119992 Moscow, Russia.
Neuroscience and Behavioral Physiology
|July 15, 2006
Abstract:
Centrally administered doses of the tripeptide corticoliberin fragment CRF(4-6) (Pro-Pro-Ile) suppressed mating behavior in male rats. Doses of 1 and 2 microg of the tripeptide produced dose-dependent increases in the latent periods of mounting, intromission, and ejaculation. Changes in measures of sexual behavior demonstrated that the corticoliberin fragment CRF(4-6) suppressed both sexual motivation and sexual performance.
