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Related Experiment Videos

Grandmultiparas in modern obstetrics.

Anwar H Nassar1, Rania Fayyumy, Wael Saab

  • 1Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.

American Journal of Perinatology
|July 15, 2006
PubMed
Summary

Grandmultiparity, defined as five or more previous deliveries, shows a trend toward increased adverse obstetrical outcomes. This includes higher risks for gestational diabetes and hypertensive disorders, though not statistically significant.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Reproductive Health

Background:

  • Grandmultiparity (≥5 previous births) is often associated with socioeconomic factors and higher BMI.
  • Previous research indicates potential risks, but data on specific complications remains varied.

Purpose of the Study:

  • To compare antenatal and intrapartum complication rates between grandmultiparas and age-matched multiparas (2-3 previous births).
  • To identify specific risks associated with grandmultiparity independent of maternal age.

Main Methods:

  • Retrospective cohort study comparing 155 grandmultiparas with 155 age-matched multiparas (1998-2003).
  • Analysis of antenatal and intrapartum complications, birth outcomes, and maternal characteristics.

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Main Results:

  • Grandmultiparas exhibited trends toward increased risks for gestational diabetes, hypertensive disorders, malpresentation, preterm delivery, and abruption.
  • No significant differences in antepartum hemorrhage, anemia, or placenta previa.
  • Intrapartum complications were similar, except for a significantly lower rate of operative vaginal delivery in grandmultiparas.
  • Birth outcomes including birthweight, macrosomia, IUGR, Apgar scores, and stillbirth rates were comparable.

Conclusions:

  • Grandmultiparity demonstrates a trend towards increased adverse obstetrical outcomes, even when controlling for maternal age.
  • While many complications did not reach statistical significance, the observed trends warrant consideration in clinical practice.