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Effect of omega-conotoxin GVIA on neurotransmitter release at the mouse neuromuscular junction
D A Protti1, L Szczupak, F S Scornik
1Instituto de Biologia Celular, Facultad de Medicina, U.B.A., Argentina.
Brain Research
|August 23, 1991
Abstract:
The effect of omega-conotoxin GVIA (omega-CgTx) was studied on spontaneous, K(+)-induced and electrically evoked neurotransmitter release at the neuromuscular junction of mouse diaphragm. omega-CgTx decreased the frequency and amplitude of basal and K(+)-induced miniature end plate potentials. This effect was abolished by raising the extracellular Ca2+ concentration. omega-CgTx had no effect on the quantal content of the electrically evoked release in this preparation.