Related Experiment Video
Updated: Aug 7, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Malignant melanoma in dermatoscopical picture]
Ceskoslovenska Patologie
|December 1, 1996
Summary
Dermatoscopy improves malignant melanoma diagnosis by 20-30%. This technique visualizes melanocytic structures, aiding in distinguishing melanoma types from other pigmented lesions.
Area of Science:
- Dermatology
- Oncology
- Dermato-histopathology
Context:
- Malignant melanoma diagnosis relies on clinical and histopathological evaluation.
- Dermatological investigation, specifically dermatoscopy, enhances diagnostic accuracy.
- Distinguishing between various melanoma subtypes and benign pigmented lesions presents a clinical challenge.
Purpose:
- To evaluate the diagnostic utility of dermatoscopy in differentiating malignant melanoma.
- To assess the visualization capabilities of dermatoscopy for melanocytic structures.
- To compare dermatoscopic findings with clinical and microscopic diagnoses.
Summary:
- Dermatoscopy improves the precision of malignant melanoma diagnosis by 20-30%.
- The technique provides clear visualization of melanocytic structures up to the dermoepidermal junction at 10x magnification.
- Dermatoscopy effectively distinguishes lentigo maligna melanoma and superficial spreading melanoma from other pigmented lesions.
Impact:
- Enhanced diagnostic accuracy for malignant melanoma.
- Improved differentiation of melanoma subtypes.
- Provides a valuable intermediate step between clinical examination and histopathology.
More Related Videos
Related Concept Videos
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:19Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...