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[Acute kidney failure caused by hantavirus infection]
T Mettang1, J Weber, U Kuhlmann
1Innere Abteilung, Robert-Bosch-Krankenhaus, Stuttgart.
Deutsche Medizinische Wochenschrift (1946)
|December 13, 1991
Summary
A patient presented with severe symptoms including fever, thrombocytopenia, and acute renal failure. Diagnosis confirmed Hantavirus infection, a rodent-borne illness with increasing European incidence.
Area of Science:
- Infectious Diseases
- Nephrology
- Virology
Background:
- Hantavirus infections, transmitted by rodents, are increasingly recognized in Central Europe.
- Hemorrhagic fever with renal syndrome (HFRS) is a severe manifestation of hantavirus infection.
Observation:
- A 37-year-old male presented with acute onset of high fever, headache, lumbar pain, marked thrombocytopenia, and moderate anemia.
- Clinical course included sinus bradycardia, upper abdominal pain (antral gastritis), subileus, splenomegaly, and acute renal failure requiring hemodialysis.
Findings:
- Serum lipase levels showed a moderate increase.
- Diagnosis was confirmed by elevated IgG and IgM antibody titers against hantavirus antigen.
Implications:
- Hantavirus infection should be considered in the differential diagnosis of acute renal failure of unknown etiology.
- Increased awareness and diagnostic consideration of hantavirus are crucial, especially with its rising incidence in Central Europe.