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Borna disease virus (BDV) infection in cats. A concise review based on current knowledge
1Northern Blood Research Centre, University of Sydney, Royal North Shore Hospital, Australia. skamhieh@yahoo.com
The Veterinary Quarterly
|July 18, 2006
Summary
Borna disease virus (BDV) infection is linked to neurological and behavioral issues in cats, with higher prevalence in affected felines. Further research is needed to understand BDV transmission and its zoonotic potential.
Area of Science:
- Veterinary Neurology
- Virology
- Epidemiology
Background:
- Persistent viral infections of the central nervous system are of significant scientific interest.
- Borna disease virus (BDV), a member of the Bornaviridae family, is implicated in neurological disorders in various animal species.
- Feline Borna disease, characterized by ataxia and behavioral changes, has been associated with BDV infection in cats.
Purpose of the Study:
- To review current knowledge regarding Borna disease virus (BDV) infection in domestic cats.
- To discuss the epidemiological aspects of BDV infection in feline populations.
- To highlight the association between BDV and neurological disorders in cats.
Main Methods:
- This review synthesizes existing literature on BDV in cats.
- Epidemiological data on BDV prevalence in feline populations were analyzed.
- Serological and molecular detection methods for BDV are discussed.
Main Results:
- BDV infection has been reported in cats, often presenting with neurological symptoms like ataxia and behavioral abnormalities.
- Studies indicate a higher prevalence of BDV detection (serological and molecular) in cats with neurological disorders compared to healthy controls.
- The transmission routes of BDV remain largely unelucidated.
Conclusions:
- BDV is a significant viral agent associated with neurological conditions in cats.
- Further investigation into BDV transmission dynamics and its potential zoonotic implications is warranted.
- Understanding the epidemiology of BDV in cats is crucial for disease management and public health.
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