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Published on: June 16, 2020
The CT appearances of sclerosing mesenteritis and associated diseases
S Y J Wat1, S Harish, A Winterbottom
1Department of Radiology, Cambridge University Hospitals Foundation NHS Trust, Cambridge, UK. josiewat@aol.com
Abstract:
Sclerosing mesenteritis is characterized by non-specific inflammation of the mesenteric fat associated with variable amount of fibrosis. The aetiology is unclear; the pathogenesis is obscure, and even its nomenclature remains variable. It is a rare condition with imaging features that can be mistaken either for a mesenteric neoplasm or for a wide variety of non-neoplastic inflammatory conditions. Knowledge of the imaging features of this condition may prevent unwarranted aggressive therapy. This review discusses the pathogenesis, clinical manifestations of this condition, as well as illustrating the characteristic computed tomography (CT) features of sclerosing mesenteritis. A rational approach to the differential diagnosis is discussed.
Insights
Sclerosing mesenteritis is a rare condition causing inflammation and fibrosis of the mesentery. Understanding its computed tomography (CT) features is crucial for accurate diagnosis and avoiding unnecessary treatments.
Area of Science:
- Gastroenterology
- Radiology
- Pathology
Background:
- Sclerosing mesenteritis involves non-specific inflammation and fibrosis of the mesenteric fat.
- Its etiology, pathogenesis, and nomenclature are not well-defined.
- Rare imaging findings can mimic mesenteric neoplasms or other inflammatory conditions.
Purpose of the Study:
- To review the pathogenesis and clinical manifestations of sclerosing mesenteritis.
- To illustrate the characteristic computed tomography (CT) features of the condition.
- To provide a rational approach to the differential diagnosis.
Main Methods:
- Literature review focusing on pathogenesis, clinical presentation, and imaging findings.
- Detailed description of computed tomography (CT) characteristics.
- Discussion of differential diagnostic considerations.
Main Results:
- Sclerosing mesenteritis presents with variable inflammation and fibrosis.
- Characteristic CT findings can aid in diagnosis.
- Distinguishing it from other conditions is essential for appropriate management.
Conclusions:
- Accurate identification of sclerosing mesenteritis through imaging is vital.
- Knowledge of CT features helps prevent misdiagnosis and inappropriate aggressive therapies.
- This review aids clinicians in the differential diagnosis of mesenteric abnormalities.
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