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Updated: Aug 7, 2026

A Model of Chronic Nutrient Infusion in the Rat
Published on: August 14, 2013
Peripheral infusion as the route of choice for intravenous nutrition: a prospective two year study
N J Everitt1, C Wong, M J McMahon
1Nutritional Support Service, University Division of Surgery, The General Infirmary at Leeds, UK.
Abstract:
A central venous catheter (CVC) is widely regarded as the standard route for delivery of intravenous nutrition (IVN). Peripheral venous infusion avoids the morbidity of a CVC, but may require regular resiting of standard intravenous cannulae, or compromise of the nutritional quality of the feed, to avoid thrombophlebitis. Fine-bore catheters, designed for use in neonates, have been associated with a much lower incidence of phlebitis when used for peripheral IVN in adults, but reports have been limited to selected groups of patients. A prospective study of 302 courses of IVN is presented in which a peripheral vein was the route of first choice. The composition of the feed was determined by the patient's metabolic requirement, and was not compromised to facilitate peripheral venous infusion. In 51% of all courses of IVN the peripheral route alone was used; 76% of patients who received peripheral IVN required only one fine-bore catheter.
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