Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

CAPweb: a bioinformatics CGH array Analysis Platform.

Stéphane Liva1, Philippe Hupé, Pierre Neuvial

  • 1Institut Curie, Service Bioinformatique 26 rue d'Ulm, 75248 Paris Cedex 05, France. capweb@curie.fr

Nucleic Acids Research
|July 18, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diffusing caveolin-1 scaffolds regulate mechanosignalling.

Nature cell biology·2026
Same author

Mesenchymal to epithelial transition (MET) in cancer progression: insights from logical modeling.

Scientific reports·2026
Same author

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma.

Cancer cell·2026
Same author

sCellST predicts single-cell gene expression from H& E images.

Nature communications·2026
Same author

NeKo: A tool for automatic network construction from prior knowledge.

PLoS computational biology·2025
Same author

Author Correction: Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms.

NPJ systems biology and applications·2025
Same journal

Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

Nucleic acids research·2026
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Correction to 'The Gene Ontology knowledgebase in 2026'.

Nucleic acids research·2026
See all related articles

A new web tool, CAPweb, simplifies the analysis of comparative genomic hybridization (CGH) array data. This user-friendly platform aids biologists in interpreting genomic variations for disease research, particularly in cancer.

Area of Science:

  • Genomics
  • Bioinformatics
  • Molecular Biology

Background:

  • DNA copy number variations are critical in diseases like cancer.
  • Array-CGH technology enables genomic-level investigation of these variations.

Purpose of the Study:

  • To introduce CAPweb, a user-friendly web tool for comprehensive array-CGH data analysis.
  • To facilitate the complete analysis workflow from raw data to biological interpretation for biologists.

Main Methods:

  • Secure upload of array-CGH image analysis results and probe annotation.
  • Automatic data normalization, breakpoint detection, and status assignment (gain, loss, normal).
  • User-guided validation, visualization, and biological interpretation of genomic profiles.

Related Experiment Videos

Main Results:

  • CAPweb provides a complete bioinformatics pipeline for array-CGH analysis.
  • The tool enables efficient data processing, including normalization and aberration detection.
  • User-friendly interface supports visualization and biological interpretation of results.

Conclusions:

  • CAPweb offers a comprehensive and accessible solution for array-CGH data analysis.
  • The platform empowers biologists to conduct in-depth genomic profiling for disease research.
  • Accessible online, CAPweb supports the complete workflow of CGH array projects.