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Updated: Aug 7, 2026

Construction of Synthetic Phage Displayed Fab Library with Tailored Diversity
Published on: May 1, 2018
Synthetic library design
1Schering AG, Medicinal Chemistry, Corporate Research, 13342 Berlin, Germany. christopher.huwe@schering.de
Abstract:
Compound libraries have an important role in the drug discovery process. Various computational methods are available as decision support tools for medicinal chemists involved in compound library synthesis programs. These methods can be used to assemble a flexible library design scheme consisting of a structure-based library design followed by property-biased library refinement and final selection according to structure-activity-relationship considerations.
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