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Pyoderma gangrenosum in a six-month-old boy
Güldane Koturoğlu1, Fadil Vardar, Ferda Ozkinay
1Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey.
Insights
Pyoderma gangrenosum (PG) is a rare skin condition. This report details the youngest infant diagnosed with PG associated with chronic recurrent multifocal osteomyelitis (CRMO).
Area of Science:
- Dermatology
- Pediatrics
- Rheumatology
Background:
- Pyoderma gangrenosum (PG) is a rare, chronic ulcerative skin condition.
- It affects all age groups, with only 4% of cases in children.
- PG is often associated with underlying systemic diseases like inflammatory bowel disease and arthritis.
Observation:
- Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition in children.
- PG has been documented with CRMO in a few pediatric cases, typically older than 18 months.
- This report presents a six-month-old boy with CRMO and associated PG.
Findings:
- The patient, a six-month-old boy, was diagnosed with CRMO.
- He also presented with pyoderma gangrenosum.
- This represents the youngest reported case of CRMO associated with PG.
Implications:
- This case highlights that CRMO can present with PG in infants under 12 months.
- It expands the known age range for this rare association.
- Early recognition and diagnosis are crucial for managing this condition in young children.
Abstract:
Pyoderma gangrenosum (PG) is an uncommon, chronic ulcerative condition of the skin that was first described in 1930. It can occur in any age group, but only 4% of the patients are infants or children. An underlying systemic disease is present in approximately 50% of the patients with PG. The most common associations include inflammatory bowel disease, arthritis, lymphoproliferative disorders and chronic recurrent multifocal osteomyelitis (CRMO). PG has been reported in association with CRMO in only a few children whose ages were between 18 months and 12 years. We report a six-month-old boy who was diagnosed as CRMO based on his clinical examination and histological findings. This is the youngest case reported in the literature (under 12 months of age) with PG associated with CRMO.
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