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Expression of vasopressin in the hypothalamus of active and passive rats with poststress depression
V I Mironova1, E A Rybnikova, V V Rakitskaya
1Laboratory of Neuroendocrinology, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg. viablos@mail.ru
Abstract:
No interstrain differences were revealed in vasopressin concentration in the hypothalamus of control and treated active and passive rats with poststress depression. Changes in vasopressin immunoreactivity corresponded to variations in corticotropin-releasing hormone concentration observed in this model of depression. These data suggest that vasopressin contributes to the development of this experimental psychopathology.
