Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis

Gautam Das1, Umesh Varshney1

  • 1Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.

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One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
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