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Related Experiment Videos

Veterans Aging Cohort Study (VACS): Overview and description.

Amy C Justice1, Elizabeth Dombrowski, Joseph Conigliaro

  • 1VA Conneticut Healthcare System, West Haven, CT 06516, USA. amy.justice2@va.gov

Medical Care
|July 20, 2006
PubMed
Summary

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The Veterans Aging Cohort Study (VACS) is a large, ongoing study examining HIV-infected and uninfected veterans. VACS provides a representative sample for analyzing health conditions in veterans with and without HIV.

Area of Science:

  • Clinical Research
  • Epidemiology
  • Public Health

Background:

  • The Veterans Aging Cohort Study (VACS) is a multisite observational study involving HIV-infected and HIV-uninfected veterans.
  • It builds upon earlier VACS 3 and VACS 5 studies, with an ongoing 8-site study.

Purpose of the Study:

  • To provide comprehensive background and context for VACS data analyses.
  • To detail the study's design, rationale, protocol, and baseline participant characteristics.

Main Methods:

  • A prospectively consented, multisite observational design was employed.
  • Data collection involved patient/provider self-reports, interviews, biological samples (blood, DNA), focus groups, and electronic medical records.

Main Results:

Related Experiment Videos

  • Over 7200 veterans have enrolled across VACS studies.
  • The 8-site VACS study enrolled 2979 HIV-infected and 3019 HIV-uninfected veterans, meeting enrollment targets.
  • VACS participants are generally older and more predominantly Black than national veteran populations.

Conclusions:

  • VACS has established a robust and representative cohort of veterans with and without HIV infection.
  • This cohort enables longitudinal research on comorbidities and AIDS-defining conditions, particularly concerning alcohol use.