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Related Experiment Videos

Intramuscular diffuse-type giant cell tumor within the hamstring muscle.

Tatsuya Yoshida1, Akio Sakamoto, Kazuhiro Tanaka

  • 1Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582 Fukuoka, Japan. yoshidat@ortho.med.kyushu-u.ac.jp

Skeletal Radiology
|July 20, 2006
PubMed
Summary

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Diffuse-type giant cell tumor (D-TGCT), also known as pigmented villonodular synovitis (PVS), can rarely occur in muscles. This case highlights PVS/D-TGCT

Area of Science:

  • Orthopedics
  • Musculoskeletal Oncology
  • Diagnostic Imaging

Background:

  • Diffuse-type giant cell tumor (D-TGCT) is synonymous with pigmented villonodular synovitis (PVS).
  • PVS typically affects large joints but can present rarely in soft tissues.
  • This report details an unusual intramuscular location of D-TGCT.

Observation:

  • A 62-year-old male incidentally discovered to have an intramuscular lesion during staging for gastric cancer.
  • The lesion, identified via positron emission tomography (PET), was resected.
  • Post-resection follow-up revealed no metastasis or recurrence over six months.

Findings:

  • The case highlights an extremely rare intramuscular location for PVS/D-TGCT.
  • The lesion exhibited a high standardized uptake value (SUV) on PET imaging.

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  • Surgical resection was curative in this instance.

    • Implications:

    • PET imaging may be a valuable tool for identifying PVS/D-TGCT, especially in atypical locations.
    • High SUV on PET scans should be considered in the differential diagnosis of intramuscular lesions.
    • This case expands the known clinical spectrum of PVS/D-TGCT and its imaging characteristics.