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Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
Published on: April 29, 2013
[Ambulatory blood pressure values in healthy children]
Insights
This study establishes normal ambulatory blood pressure (ABP) values for children aged 4-6 years. Findings provide preliminary reference ranges for daytime and nighttime systolic and diastolic blood pressure in this age group.
Area of Science:
- Pediatric Cardiology
- Clinical Physiology
Context:
- Childhood hypertension diagnosis relies on ambulatory blood pressure monitoring (ABPM).
- Normal ABPM values for children aged 4-6 years (height 100-120 cm) are not well-established.
- Establishing normative data is crucial for accurate hypertension diagnosis in pediatric populations.
Purpose:
- To determine normal ambulatory blood pressure (ABP) ranges in children aged 4-6 years with body heights between 100 and 120 cm.
- To provide a preliminary reference for daytime and nighttime blood pressure readings in this specific pediatric cohort.
- To assess diurnal variations in blood pressure and heart rate.
Summary:
- 40 normotensive children (4-6 years) underwent 24-hour ABPM using an oscillometric device.
- Mean daytime SBP/DBP: boys 108/67 mmHg, girls 105/66 mmHg.
- Mean nighttime SBP/DBP: boys 98/56 mmHg, girls 97/56 mmHg.
- Significant differences observed between day and night readings, indicating a nocturnal fall.
Impact:
- Provides essential preliminary reference data for pediatric ambulatory blood pressure monitoring.
- Highlights the need for larger, multicenter studies to establish definitive normal ABP ranges for children.
- Aids clinicians in the accurate diagnosis and management of hypertension in young children.
Abstract:
Ambulatory blood pressure monitoring (ABPM) is an important tool in the diagnosis and management of childhood hypertension. Normal ambulatory blood pressure (ABP) values in children with body heights between 100 and 120 cm have not been reported. The aim of the study was to establish the normal range of values for ABPM in these children. 24-hour ABPM was performed in 40 normotensive (auscultatory casual blood pressure was obtained before ABPM) subjects, aged from 4 to 6 years (26 males, 14 females) with body heights between 95 and 125 cm. ABPM was carried out on non-dominant arm using the oscillometric device (SpaceLab 90207) with appropriate cuff size. The monitor was programmed to measure BP every 15 min. during the day (6 a.m. to 10 p.m.) and every 30 min. during the night (10 p.m. to 6 a.m.). The mean daytime SBP/DBP in boys and girls was 108+/-6/67+/-5 and 105+/-5/66+/-1, respectively. The mean nighttime SBP/DBP in boys and girls was 98+/6/56+/-5 and 97+/-7/56+/-4, respectively. There was a significant difference between day and night readings of SBP, DBP and heart rate (nocturnal fall was observed). The distribution of ABP noted in this study could serve as preliminary reference. A multicenter study should be performed to provide normal ranges of ABP.
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