Related Experiment Video
Updated: Aug 7, 2026

Immunolabelling Myofiber Degeneration in Muscle Biopsies
Published on: December 5, 2019
[Fibronectin immunohistochemical staining for diagnosing sudden death caused by viral myocarditis]
Wen-Sheng Li1, Qing-Jin Gong, Long-Wu Lu
1The Bureau of Public Security of Gongbei, Zhuhai 519020, China.
Objective:
To study the value of Fibronectin(Fn) immunohistochemical staining for diagnosing slight viral myocarditis.
Methods:
The heart samples of human with myocarditis were studied by using LSAB immunohistochemical staining with anti-fibronectin antibody.
Results:
Dense deposition was found in the myocardium of human with myocarditis. Some Fn-positive cardiomyocytes were observed.
Conclusion:
Slight degeneration of cardiomyocytes could be identified by Fn-LSAB immunohistochemical staining and Fn-deposition is one of the reliable marks for inflammation in the myocardium.
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